t(1;16)(q12;q24)
2000-02-01 Jean-Loup Huret Affiliation1.Genetics, Dept Medical Information, University of Poitiers, CHU Poitiers Hospital, F-86021 Poitiers, France
Clinics and Pathology
Disease
Acute myeloid leukemia (AML)
Note
poorly known: only 2 cases to date
Phenotype stem cell origin
a case of Fanconi anemia and a case of M1-AML
Epidemiology
The Fanconi anemia patient was a 9 yr old girl, and the AML case was a 22 yr old male patient
Prognosis
unknown
Genes Involved and Proteins
Article Bibliography
| Pubmed ID | Last Year | Title | Authors |
|---|---|---|---|
| 10602418 | 1999 | Fluorescence in situ hybridization analysis of chromosome 1 abnormalities in hematopoietic disorders: rearrangements of DNA satellite II and new recurrent translocations. | Busson-Le Coniat M et al |
Summary
t(1;16)(q12;q24) Fluorescence in situ hybridization with Vysis LSI 1p36/LSI 1q25 dual-color probe (Abbott molecular, US) showing extra copy of 1q25 on metaphase with der(16)t(1;16) (green signal on der(16) chromosome) u2013 Courtesy Adriana Zamecnikova.
Citation
Jean-Loup Huret
t(1;16)(q12;q24)
Atlas Genet Cytogenet Oncol Haematol. 2000-02-01
Online version: http://atlasgeneticsoncology.org/haematological/1318/t(1
