inv(6)(p25q13)

2008-11-01   Jean-Loup Huret 

1.Genetics, Dept Medical Information, University of Poitiers; CHU Poitiers Hospital, F-86021 Poitiers, France

Clinics and Pathology

Disease

Myeloid malignancies

Epidemiology

Only 2 cases to date, a 62-year-old male patient with a refractory anemia with excess of blasts (RAEB), and a patient with a treatment related myelodysplastic syndrome evolving to overt leukaemia (Davis et al., 1984; Olney et al., 2002).

Prognosis

The patient with RAEB died one month after diagnosis.

Genes Involved and Proteins

Note
The genes involved in this anomaly are unknown.

Bibliography

Pubmed IDLast YearTitleAuthors
67133601984Hematologic manifestations associated with deletions of the long arm of chromosome 20.Davis MP et al
119212752002Unique balanced chromosome abnormalities in treatment-related myelodysplastic syndromes and acute myeloid leukemia: report from an international workshop.Olney HJ et al

Citation

Jean-Loup Huret

inv(6)(p25q13)

Atlas Genet Cytogenet Oncol Haematol. 2008-11-01

Online version: http://atlasgeneticsoncology.org/haematological/1529/inv(6)(p25q13)

External Links