BCAN/NTRK1 (1q23)

0000-00-00   Jean-Loup Huret  , Philippe Dessen  

(Note: the fusion was discovered by NGS. Many chromosome rearrangement mechanisms such as translocation, inversion,deletion or complex rearrangement may lead to the same fusion)

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to u00a0How to contribute

Summary

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to  How to contribute

Genes Involved and Proteins

Gene name

Location

1q23.1

Gene name

Location

1q23.1

Highly cited references

Pubmed IDYearTitleCitations
296542292018Somatic genome editing with the RCAS-TVA-CRISPR-Cas9 system for precision tumor modeling.73
348630952021Discovery of clinically relevant fusions in pediatric cancer.60
286958882017Somatic chromosomal engineering identifies BCAN-NTRK1 as a potent glioma driver and therapeutic target.37
298726942017Clinical and radiographic response following targeting of BCAN-NTRK1 fusion in glioneuronal tumor.26
295327922018Author Correction: Somatic chromosomal engineering identifies BCAN-NTRK1 as a potent glioma driver and therapeutic target.0

Article Bibliography

Pubmed IDLast YearTitleAuthors
239174012013The integrated landscape of driver genomic alterations in glioblastoma.Frattini V et al
242619842013Exploration of the gene fusion landscape of glioblastoma using transcriptome sequencing and copy number data.Shah N et al

Citation

Jean-Loup Huret ; Philippe Dessen

BCAN/NTRK1 (1q23)

Atlas Genet Cytogenet Oncol Haematol. 0000-00-00

Online version: http://atlasgeneticsoncology.org/solid-tumor/103943/bcan-ntrk1-(1q23)