t(1;10)(p13;q11) TRIM33/RET

0000-00-00   Jean-Loup Huret  , Philippe Dessen  

(Note: the fusion was discovered by NGS. Many chromosome rearrangement mechanisms such as translocation, inversion,deletion or complex rearrangement may lead to the same fusion)

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to u00a0How to contribute

Summary

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to  How to contribute

Genes Involved and Proteins

Gene name

Location

1p13.2

Gene name

Location

10q11.21

Highly cited references

Pubmed IDYearTitleCitations
371826022023Combination Therapy With MDM2 and MEK Inhibitors Is Effective in Patient-Derived Models of Lung Adenocarcinoma With Concurrent Oncogenic Drivers and MDM2 Amplification.58
367042822023Comparison of ultrasonography and pathology features between children and adolescents with papillary thyroid carcinoma.38
331351962021Oncocytic intraductal carcinoma of salivary glands: a distinct variant with TRIM33-RET fusions and BRAF V600E mutations.34
396149572024Clinicopathological, Prognostic and Molecular Profile of Salivary Gland Intraductal Carcinoma: A Systematic Review.33
389351972024Pure Apocrine Intraductal Carcinoma of Salivary Glands: Reassessment of Molecular Underpinnings and Behavior.29
349856832022Frankly Invasive Carcinoma Ex-intraductal Carcinoma: Expanding on an Emerging and Perplexing Concept in Salivary Gland Tumor Pathology.27
235332642013Response to Cabozantinib in patients with RET fusion-positive lung adenocarcinomas.26
371391482023RET rearrangement-positive pancreatic cancer has remarkable response to pralsetinib: a case report.25
317621462020Next-generation sequencing in salivary gland carcinoma: Targetable alterations lead to a therapeutic advantage-Multicenter experience.0

Article Bibliography

Pubmed IDLast YearTitleAuthors
104390471999The transcription coactivator HTIF1 and a related protein are fused to the RET receptor tyrosine kinase in childhood papillary thyroid carcinomas.Klugbauer S et al
107417392000Pattern of radiation-induced RET and NTRK1 rearrangements in 191 post-chernobyl papillary thyroid carcinomas: biological, phenotypic, and clinical implications.Rabes HM et al

Citation

Jean-Loup Huret ; Philippe Dessen

t(1;10)(p13;q11) TRIM33/RET

Atlas Genet Cytogenet Oncol Haematol. 0000-00-00

Online version: http://atlasgeneticsoncology.org/solid-tumor/104091/t(1