Nasopharyngeal tumors
2025-03-05 Paola Dal Cin, PhD Affiliation1.Brigham and Women's Hospital , Harvard Medical School, Boston , MA (USA)
Classification
Definition
They can be either hamartomas (hairy polyp and salivary gland anlage tumor) or carcinomas (low-grade papillary nasopharyngeal adenocarcinoma and nasopharyngeal carcinoma).
So far, the lack of apparent driver mutations in 3 salivary gland anlage tumors, rare pediatric condition, supports the classification of a hamartoma (nonneoplastic) process. 1
A single case of papillary nasopharyngeal adenocarcinoma harbor with a GOPC::ROS1. 2 Similar fusions has been reported in a variety gliomas type. 3
Article Bibliography
| Reference Number | Pubmed ID | Last Year | Title | Authors |
|---|---|---|---|---|
| 1 | 30598408 | 2019 | Salivary gland anlage tumor: molecular profiling sheds light on a morphologic question. | Peters SM et al |
| 2 | 33546077 | 2021 | Nasopharyngeal papillary adenocarcinoma harboring a fusion of ROS1 with GOPC: A case report. | Wang J et al |
| 3 | 34536122 | 2021 | GOPC:ROS1 and other ROS1 fusions represent a rare but recurrent drug target in a variety of glioma types. | Sievers P et al |
Citation
Paola Dal Cin, PhD
Nasopharyngeal tumors
Atlas Genet Cytogenet Oncol Haematol. 2025-03-05
Online version: http://atlasgeneticsoncology.org/solid-tumor/209312/nasopharyngeal-tumors
