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Breast Cancer Res Treat. 2003 Aug;80(3):347-52. |
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J Biol Chem. 1999 Sep 17;274(38):27092-8. |
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Cell. 2007 May 18;129(4):823-37. |
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Cell. 1999 Aug 6;98(3):387-96. |
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Cell Cycle. 2007 Feb 15;6(4):450-4. Epub 2007 Feb 12. |
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The molecular function and clinical phenotype of partial deletions of the IGF2/H19 imprinting control region depends on the spatial arrangement of the remaining CTCF-binding sites. |
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Hum Mol Genet. 2013 Feb 1;22(3):544-57. doi: 10.1093/hmg/dds465. Epub 2012 Oct 30. |
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Mol Syst Biol. 2010 Nov 2;6:426. doi: 10.1038/msb.2010.79. |
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CTCF binding and higher order chromatin structure of the H19 locus are maintained in mitotic chromatin. |
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EMBO J. 2005 Sep 21;24(18):3291-300. Epub 2005 Aug 18. |
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Epigenetic inactivation of BRCA1 is associated with aberrant expression of CTCF and DNA methyltransferase (DNMT3B) in some sporadic breast tumours. |
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Eur J Cancer. 2007 Jan;43(1):210-9. Epub 2006 Oct 27. |
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CTCF, a candidate trans-acting factor for X-inactivation choice. |
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Science. 2002 Jan 11;295(5553):345-7. Epub 2001 Dec 6. |
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Curr Opin Immunol. 2012 Apr;24(2):153-9. doi: 10.1016/j.coi.2012.01.003. Epub 2012 Mar 15. (REVIEW) |
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PLoS One. 2012;7(7):e41374. doi: 10.1371/journal.pone.0041374. Epub 2012 Jul 19. |
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CDC25B mediates rapamycin-induced oncogenic responses in cancer cells. |
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Cancer Res. 2009 Mar 15;69(6):2663-8. Epub 2009 Mar 10. |
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Integration of external signaling pathways with the core transcriptional network in embryonic stem cells. |
Chen X, Xu H, Yuan P, Fang F, Huss M, Vega VB, Wong E, Orlov YL, Zhang W, Jiang J, Loh YH, Yeo HC, Yeo ZX, Narang V, Govindarajan KR, Leong B, Shahab A, Ruan Y, Bourque G, Sung WK, Clarke ND, Wei CL, Ng HH. |
Cell. 2008 Jun 13;133(6):1106-17. |
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CTCF interacts with and recruits the largest subunit of RNA polymerase II to CTCF target sites genome-wide. |
Chernukhin I, Shamsuddin S, Kang SY, Bergstrom R, Kwon YW, Yu W, Whitehead J, Mukhopadhyay R, Docquier F, Farrar D, Morrison I, Vigneron M, Wu SY, Chiang CM, Loukinov D, Lobanenkov V, Ohlsson R, Klenova E. |
Mol Cell Biol. 2007 Mar;27(5):1631-48. Epub 2007 Jan 8. |
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Antisense transcription and heterochromatin at the DM1 CTG repeats are constrained by CTCF. |
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Mol Cell. 2005 Nov 11;20(3):483-9. |
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Lysine acetylation targets protein complexes and co-regulates major cellular functions. |
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Science. 2009 Aug 14;325(5942):834-40. Epub 2009 Jul 16. |
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Global analysis of the insulator binding protein CTCF in chromatin barrier regions reveals demarcation of active and repressive domains. |
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Genome Res. 2009 Jan;19(1):24-32. Epub 2008 Dec 3. |
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Loss of imprinting of insulin-like growth factor-II in Wilms' tumor commonly involves altered methylation but not mutations of CTCF or its binding site. |
Cui H, Niemitz EL, Ravenel JD, Onyango P, Brandenburg SA, Lobanenkov VV, Feinberg AP. |
Cancer Res. 2001 Jul 1;61(13):4947-50. |
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Frequent aberrant methylation of the imprinted IGF2/H19 locus and LINE1 hypomethylation in ovarian carcinoma. |
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Int J Oncol. 2010 Jan;36(1):171-9. |
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Gain of DNA methylation is enhanced in the absence of CTCF at the human retinoblastoma gene promoter. |
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BMC Cancer. 2011 Jun 10;11:232. doi: 10.1186/1471-2407-11-232. |
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H19-DMR allele-specific methylation analysis reveals epigenetic heterogeneity of CTCF binding site 6 but not of site 5 in head-and-neck carcinomas: a pilot case-control analysis. |
De Castro Valente Esteves LI, De Karla Cervigne N, Do Carmo Javaroni A, Magrin J, Kowalski LP, Rainho CA, Rogatto SR. |
Int J Mol Med. 2006 Feb;17(2):397-404. |
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Epigenetic regulation of the human retinoblastoma tumor suppressor gene promoter by CTCF. |
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Cancer Res. 2007 Mar 15;67(6):2577-85 |
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The human enhancer blocker CTC-binding factor interacts with the transcription factor Kaiso. |
Defossez PA, Kelly KF, Filion GJ, Perez-Torrado R, Magdinier F, Menoni H, Nordgaard CL, Daniel JM, Gilson E. |
J Biol Chem. 2005 Dec 30;280(52):43017-23. Epub 2005 Oct 17. |
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Differential expression and phosphorylation of CTCF, a c-myc transcriptional regulator, during differentiation of human myeloid cells. |
Delgado MD, Chernukhin IV, Bigas A, Klenova EM, Leon J. |
FEBS Lett. 1999 Feb 5;444(1):5-10. |
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CTCF promotes muscle differentiation by modulating the activity of myogenic regulatory factors. |
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J Biol Chem. 2011 Apr 8;286(14):12483-94. doi: 10.1074/jbc.M110.164574. Epub 2011 Feb 2. |
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A role for CTCF and cohesin in subtelomere chromatin organization, TERRA transcription, and telomere end protection. |
Deng Z, Wang Z, Stong N, Plasschaert R, Moczan A, Chen HS, Hu S, Wikramasinghe P, Davuluri RV, Bartolomei MS, Riethman H, Lieberman PM. |
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Topological domains in mammalian genomes identified by analysis of chromatin interactions. |
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Nature. 2012 Apr 11;485(7398):376-80. doi: 10.1038/nature11082. |
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Decreased poly(ADP-ribosyl)ation of CTCF, a transcription factor, is associated with breast cancer phenotype and cell proliferation. |
Docquier F, Kita GX, Farrar D, Jat P, O'Hare M, Chernukhin I, Gretton S, Mandal A, Alldridge L, Klenova E. |
Clin Cancer Res. 2009 Sep 15;15(18):5762-71. Epub 2009 Sep 8. |
PMID 19737964 |
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Commonly altered genomic regions in acute myeloid leukemia are enriched for somatic mutations involved in chromatin remodeling and splicing. |
Dolnik A, Engelmann JC, Scharfenberger-Schmeer M, Mauch J, Kelkenberg-Schade S, Haldemann B, Fries T, Kronke J, Kuhn MW, Paschka P, Kayser S, Wolf S, Gaidzik VI, Schlenk RF, Rucker FG, Dohner H, Lottaz C, Dohner K, Bullinger L. |
Blood. 2012 Nov 1;120(18):e83-92. doi: 10.1182/blood-2011-12-401471. Epub 2012 Sep 13. |
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Identification of a Ctcf cofactor, Yy1, for the X chromosome binary switch. |
Donohoe ME, Zhang LF, Xu N, Shi Y, Lee JT. |
Mol Cell. 2007 Jan 12;25(1):43-56. |
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The insulator binding protein CTCF associates with the nuclear matrix. |
Dunn KL, Zhao H, Davie JR. |
Exp Cell Res. 2003 Aug 1;288(1):218-23. |
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Regulation of the transcription factor, CTCF, by phosphorylation with protein kinase CK2. |
El-Kady A, Klenova E. |
FEBS Lett. 2005 Feb 28;579(6):1424-34. |
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DNA methylation in the CTCF-binding site I and the expression pattern of the H19 gene: does positive expression predict poor prognosis in early stage head and neck carcinomas? |
Esteves LI, Javaroni AC, Nishimoto IN, Magrin J, Squire JA, Kowalski LP, Rainho CA, Rogatto SR. |
Mol Carcinog. 2005 Oct;44(2):102-10. |
PMID 16015666 |
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Mutational analysis of the poly(ADP-ribosyl)ation sites of the transcription factor CTCF provides an insight into the mechanism of its regulation by poly(ADP-ribosyl)ation. |
Farrar D, Rai S, Chernukhin I, Jagodic M, Ito Y, Yammine S, Ohlsson R, Murrell A, Klenova E. |
Mol Cell Biol. 2010 Mar;30(5):1199-216. Epub 2009 Dec 28. |
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Transgenic RNAi reveals essential function for CTCF in H19 gene imprinting. |
Fedoriw AM, Stein P, Svoboda P, Schultz RM, Bartolomei MS. |
Science. 2004 Jan 9;303(5655):238-40. |
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Genetics and epigenetics of the multifunctional protein CTCF. |
Filippova GN. |
Curr Top Dev Biol. 2008;80:337-60. (REVIEW) |
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The tumor suppressor role of CTCF. |
Fiorentino FP, Giordano A. |
J Cell Physiol. 2012 Feb;227(2):479-92. doi: 10.1002/jcp.22780. (REVIEW) |
PMID 21465478 |
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Allele-specific binding of CTCF to the multipartite imprinting control region KvDMR1. |
Fitzpatrick GV, Pugacheva EM, Shin JY, Abdullaev Z, Yang Y, Khatod K, Lobanenkov VV, Higgins MJ. |
Mol Cell Biol. 2007 Apr;27(7):2636-47. Epub 2007 Jan 22. |
PMID 17242189 |
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Aging and cancer-related loss of insulin-like growth factor 2 imprinting in the mouse and human prostate. |
Fu VX, Dobosy JR, Desotelle JA, Almassi N, Ewald JA, Srinivasan R, Berres M, Svaren J, Weindruch R, Jarrard DF. |
Cancer Res. 2008a Aug 15;68(16):6797-802. |
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The insulator binding protein CTCF positions 20 nucleosomes around its binding sites across the human genome. |
Fu Y, Sinha M, Peterson CL, Weng Z. |
PLoS Genet. 2008b Jul 25;4(7):e1000138. |
PMID 18654629 |
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Functional role of CCCTC binding factor in insulin-stimulated cell proliferation. |
Gao J, Li T, Lu L. |
Cell Prolif. 2007 Dec;40(6):795-808. |
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Targeted deletion of multiple CTCF-binding elements in the human C-MYC gene reveals a requirement for CTCF in C-MYC expression. |
Gombert WM, Krumm A. |
PLoS One. 2009 Jul 1;4(7):e6109. |
PMID 19568426 |
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Gene-specific repression of the p53 target gene PUMA via intragenic CTCF-Cohesin binding. |
Gomes NP, Espinosa JM. |
Genes Dev. 2010 May 15;24(10):1022-34. |
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Loss of imprinting of IGF2 and H19, loss of heterozygosity of IGF2R and CTCF, and Helicobacter pylori infection in laryngeal squamous cell carcinoma. |
Grbesa I, Marinkovic M, Ivkic M, Kruslin B, Novak-Kujundzic R, Pegan B, Bogdanovic O, Bedekovic V, Gall-Troselj K. |
J Mol Med. 2008 Sep;86(9):1057-66. Epub 2008 Jul 5. |
PMID 18604514 |
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Loss of expression of chromosome 16q genes DPEP1 and CTCF in lobular carcinoma in situ of the breast. |
Green AR, Krivinskas S, Young P, Rakha EA, Paish EC, Powe DG, Ellis IO. |
Breast Cancer Res Treat. 2009 Jan;113(1):59-66. Epub 2008 Jan 23. |
PMID 18213475 |
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ADP-ribose polymer depletion leads to nuclear Ctcf re-localization and chromatin rearrangement(1). |
Guastafierro T, Catizone A, Calabrese R, Zampieri M, Martella O, Bacalini MG, Reale A, Di Girolamo M, Miccheli M, Farrar D, Klenova E, Ciccarone F, Caiafa P. |
Biochem J. 2013 Feb 1;449(3):623-30. doi: 10.1042/BJ20121429. |
PMID 23116180 |
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Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions. |
Guelen L, Pagie L, Brasset E, Meuleman W, Faza MB, Talhout W, Eussen BH, de Klein A, Wessels L, de Laat W, van Steensel B. |
Nature. 2008 Jun 12;453(7197):948-51. doi: 10.1038/nature06947. Epub 2008 May 7. |
PMID 18463634 |
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CTCF-binding elements mediate control of V(D)J recombination. |
Guo C, Yoon HS, Franklin A, Jain S, Ebert A, Cheng HL, Hansen E, Despo O, Bossen C, Vettermann C, Bates JG, Richards N, Myers D, Patel H, Gallagher M, Schlissel MS, Murre C, Busslinger M, Giallourakis CC, Alt FW. |
Nature. 2011 Sep 11;477(7365):424-30. doi: 10.1038/nature10495. |
PMID 21909113 |
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A CTCF-binding silencer regulates the imprinted genes AWT1 and WT1-AS and exhibits sequential epigenetic defects during Wilms' tumourigenesis. |
Hancock AL, Brown KW, Moorwood K, Moon H, Holmgren C, Mardikar SH, Dallosso AR, Klenova E, Loukinov D, Ohlsson R, Lobanenkov VV, Malik K. |
Hum Mol Genet. 2007 Feb 1;16(3):343-54. Epub 2007 Jan 8. |
PMID 17210670 |
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CTCF-mediated functional chromatin interactome in pluripotent cells. |
Handoko L, Xu H, Li G, Ngan CY, Chew E, Schnapp M, Lee CW, Ye C, Ping JL, Mulawadi F, Wong E, Sheng J, Zhang Y, Poh T, Chan CS, Kunarso G, Shahab A, Bourque G, Cacheux-Rataboul V, Sung WK, Ruan Y, Wei CL. |
Nat Genet. 2011 Jun 19;43(7):630-8. doi: 10.1038/ng.857. |
PMID 21685913 |
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CTCF regulates cell cycle progression of alphabeta T cells in the thymus. |
Heath H, Ribeiro de Almeida C, Sleutels F, Dingjan G, van de Nobelen S, Jonkers I, Ling KW, Gribnau J, Renkawitz R, Grosveld F, Hendriks RW, Galjart N. |
EMBO J. 2008 Nov 5;27(21):2839-50. Epub 2008 Oct 16. |
PMID 18923423 |
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The chromatin insulator CTCF and the emergence of metazoan diversity. |
Heger P, Marin B, Bartkuhn M, Schierenberg E, Wiehe T. |
Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17507-12. doi: 10.1073/pnas.1111941109. Epub 2012 Oct 8. |
PMID 23045651 |
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The evolution of epigenetic regulators CTCF and BORIS/CTCFL in amniotes. |
Hore TA, Deakin JE, Marshall Graves JA. |
PLoS Genet. 2008 Aug 29;4(8):e1000169. |
PMID 18769711 |
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Cell type specificity of chromatin organization mediated by CTCF and cohesin. |
Hou C, Dale R, Dean A. |
Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3651-6. Epub 2010 Feb 2. |
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CTCF-dependent enhancer-blocking by alternative chromatin loop formation. |
Hou C, Zhao H, Tanimoto K, Dean A. |
Proc Natl Acad Sci U S A. 2008 Dec 23;105(51):20398-403. Epub 2008 Dec 12. |
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CTCF-dependent chromatin insulator is linked to epigenetic remodeling. |
Ishihara K, Oshimura M, Nakao M. |
Mol Cell. 2006 Sep 1;23(5):733-42. |
PMID 16949368 |
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Analysis of the vertebrate insulator protein CTCF-binding sites in the human genome. |
Kim TH, Abdullaev ZK, Smith AD, Ching KA, Loukinov DI, Green RD, Zhang MQ, Lobanenkov VV, Ren B. |
Cell. 2007 Mar 23;128(6):1231-45. |
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Sumoylation modulates a domain in CTCF that activates transcription and decondenses chromatin. |
Kitchen NS, Schoenherr CJ. |
J Cell Biochem. 2010 Oct 15;111(3):665-75. |
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Functional phosphorylation sites in the C-terminal region of the multivalent multifunctional transcriptional factor CTCF. |
Klenova EM, Chernukhin IV, El-Kady A, Lee RE, Pugacheva EM, Loukinov DI, Goodwin GH, Delgado D, Filippova GN, Leon J, Morse HC 3rd, Neiman PE, Lobanenkov VV. |
Mol Cell Biol. 2001 Mar;21(6):2221-34. |
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DNA methylation prevents CTCF-mediated silencing of the oncogene BCL6 in B cell lymphomas. |
Lai AY, Fatemi M, Dhasarathy A, Malone C, Sobol SE, Geigerman C, Jaye DL, Mav D, Shah R, Li L, Wade PA. |
J Exp Med. 2010 Aug 30;207(9):1939-50. Epub 2010 Aug 23. |
PMID 20733034 |
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XPG and XPF endonucleases trigger chromatin looping and DNA demethylation for accurate expression of activated genes. |
Le May N, Fradin D, Iltis I, Bougneres P, Egly JM. |
Mol Cell. 2012 Aug 24;47(4):622-32. doi: 10.1016/j.molcel.2012.05.050. Epub 2012 Jul 5. |
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CTCF regulates allelic expression of Igf2 by orchestrating a promoter-polycomb repressive complex 2 intrachromosomal loop. |
Li T, Hu JF, Qiu X, Ling J, Chen H, Wang S, Hou A, Vu TH, Hoffman AR. |
Mol Cell Biol. 2008 Oct;28(20):6473-82. Epub 2008 Jul 28. |
PMID 18662993 |
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Functional role of CCCTC binding factor (CTCF) in stress-induced apoptosis. |
Li T, Lu L. |
Exp Cell Res. 2007 Aug 15;313(14):3057-65. Epub 2007 May 24. |
PMID 17583694 |
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CTCF cis-regulates trinucleotide repeat instability in an epigenetic manner: a novel basis for mutational hot spot determination. |
Libby RT, Hagerman KA, Pineda VV, Lau R, Cho DH, Baccam SL, Axford MM, Cleary JD, Moore JM, Sopher BL, Tapscott SJ, Filippova GN, Pearson CE, La Spada AR. |
LoS Genet. 2008 Nov;4(11):e1000257. Epub 2008 Nov 14. |
PMID 19008940 |
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CTCF mediates interchromosomal colocalization between Igf2/H19 and Wsb1/Nf1. |
Ling JQ, Li T, Hu JF, Vu TH, Chen HL, Qiu XW, Cherry AM, Hoffman AR. |
Science. 2006 Apr 14;312(5771):269-72. |
PMID 16614224 |
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Transvection mediated by the translocated cyclin D1 locus in mantle cell lymphoma. |
Liu H, Huang J, Wang J, Jiang S, Bailey AS, Goldman DC, Welcker M, Bedell V, Slovak ML, Clurman B, Thayer M, Fleming WH, Epner E. |
J Exp Med. 2008 Aug 4;205(8):1843-58. Epub 2008 Jul 14. |
PMID 18625744 |
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BORIS, a novel male germ-line-specific protein associated with epigenetic reprogramming events, shares the same 11-zinc-finger domain with CTCF, the insulator protein involved in reading imprinting marks in the soma. |
Loukinov DI, Pugacheva E, Vatolin S, Pack SD, Moon H, Chernukhin I, Mannan P, Larsson E, Kanduri C, Vostrov AA, Cui H, Niemitz EL, Rasko JE, Docquier FM, Kistler M, Breen JJ, Zhuang Z, Quitschke WW, Renkawitz R, Klenova EM, Feinberg AP, Ohlsson R, Morse HC 3rd, Lobanenkov VV. |
Proc Natl Acad Sci U S A. 2002 May 14;99(10):6806-11. |
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NF-kappaB subtypes regulate CCCTC binding factor affecting corneal epithelial cell fate. |
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J Biol Chem. 2010 Mar 26;285(13):9373-82. Epub 2010 Jan 28. |
PMID 20110362 |
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Thyroid hormone-regulated enhancer blocking: cooperation of CTCF and thyroid hormone receptor. |
Lutz M, Burke LJ, LeFevre P, Myers FA, Thorne AW, Crane-Robinson C, Bonifer C, Filippova GN, Lobanenkov V, Renkawitz R. |
EMBO J. 2003 Apr 1;22(7):1579-87. |
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The CTCF insulator protein is posttranslationally modified by SUMO. |
MacPherson MJ, Beatty LG, Zhou W, Du M, Sadowski PD. |
Mol Cell Biol. 2009 Feb;29(3):714-25. Epub 2008 Nov 24. |
PMID 19029252 |
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A search for a mammalian homologue of the Drosophila photoreceptor development gene glass yields Zfp64, a zinc finger encoding gene which maps to the distal end of mouse chromosome 2. |
Mack HG, Beck F, Bowtell DD. |
Gene. 1997 Jan 31;185(1):11-7. |
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The insulator factor CTCF controls MHC class II gene expression and is required for the formation of long-distance chromatin interactions. |
Majumder P, Gomez JA, Chadwick BP, Boss JM. |
J Exp Med. 2008 Apr 14;205(4):785-98. Epub 2008 Mar 17. |
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CTCF and cohesin: linking gene regulatory elements with their targets. |
Merkenschlager M, Odom DT. |
Cell. 2013 Mar 14;152(6):1285-97. doi: 10.1016/j.cell.2013.02.029. (REVIEW) |
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Role of CCCTC binding factor (CTCF) and cohesin in the generation of single-cell diversity of protocadherin-? gene expression. |
Monahan K, Rudnick ND, Kehayova PD, Pauli F, Newberry KM, Myers RM, Maniatis T. |
Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):9125-30. doi: 10.1073/pnas.1205074109. Epub 2012 May 1. |
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CTCF is conserved from Drosophila to humans and confers enhancer blocking of the Fab-8 insulator. |
Moon H, Filippova G, Loukinov D, Pugacheva E, Chen Q, Smith ST, Munhall A, Grewe B, Bartkuhn M, Arnold R, Burke LJ, Renkawitz-Pohl R, Ohlsson R, Zhou J, Renkawitz R, Lobanenkov V. |
EMBO Rep. 2005 Feb;6(2):165-70. |
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YY1 associates with the macrosatellite DXZ4 on the inactive X chromosome and binds with CTCF to a hypomethylated form in some male carcinomas. |
Moseley SC, Rizkallah R, Tremblay DC, Anderson BR, Hurt MM, Chadwick BP. |
Nucleic Acids Res. 2012 Feb;40(4):1596-608. doi: 10.1093/nar/gkr964. Epub 2011 Nov 7. |
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The binding sites for the chromatin insulator protein CTCF map to DNA methylation-free domains genome-wide. |
Mukhopadhyay R, Yu W, Whitehead J, Xu J, Lezcano M, Pack S, Kanduri C, Kanduri M, Ginjala V, Vostrov A, Quitschke W, Chernukhin I, Klenova E, Lobanenkov V, Ohlsson R. |
Genome Res. 2004 Aug;14(8):1594-602. Epub 2004 Jul 15. |
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Mummert SK, Lobanenkov VA, Feinberg AP. |
Genes Chromosomes Cancer. 2005 Jun;43(2):155-61. |
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Loss of imprinting of the insulin-like growth factor II gene occurs by biallelic methylation in a core region of H19-associated CTCF-binding sites in colorectal cancer. |
Nakagawa H, Chadwick RB, Peltomaki P, Plass C, Nakamura Y, de La Chapelle A. |
Proc Natl Acad Sci U S A. 2001 Jan 16;98(2):591-6. Epub 2000 Dec 19. |
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Adaptive evolution and the birth of CTCF binding sites in the Drosophila genome. |
Ni X, Zhang YE, Negre N, Chen S, Long M, White KP. |
PLoS Biol. 2012;10(11):e1001420. doi: 10.1371/journal.pbio.1001420. Epub 2012 Nov 6. |
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Identification of a perinuclear positioning element in human subtelomeres that requires A-type lamins and CTCF. |
Ottaviani A, Schluth-Bolard C, Rival-Gervier S, Boussouar A, Rondier D, Foerster AM, Morere J, Bauwens S, Gazzo S, Callet-Bauchu E, Gilson E, Magdinier F. |
EMBO J. 2009 Aug 19;28(16):2428-36. Epub 2009 Jul 30. |
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Aberrant epigenetic modifications in the CTCF binding domain of the IGF2/H19 gene in prostate cancer compared with benign prostate hyperplasia. |
Paradowska A, Fenic I, Konrad L, Sturm K, Wagenlehner F, Weidner W, Steger K. |
Int J Oncol. 2009 Jul;35(1):87-96. |
PMID 19513555 |
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Cohesins functionally associate with CTCF on mammalian chromosome arms. |
Parelho V, Hadjur S, Spivakov M, Leleu M, Sauer S, Gregson HC, Jarmuz A, Canzonetta C, Webster Z, Nesterova T, Cobb BS, Yokomori K, Dillon N, Aragon L, Fisher AG, Merkenschlager M. |
Cell. 2008 Feb 8;132(3):422-33. Epub 2008 Jan 31. |
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CTCF: master weaver of the genome. |
Phillips JE, Corces VG. |
Cell. 2009 Jun 26;137(7):1194-211. (REVIEW) |
PMID 19563753 |
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Microdeletion of target sites for insulator protein CTCF in a chromosome 11p15 imprinting center in Beckwith-Wiedemann syndrome and Wilms' tumor. |
Prawitt D, Enklaar T, Gartner-Rupprecht B, Spangenberg C, Oswald M, Lausch E, Schmidtke P, Reutzel D, Fees S, Lucito R, Korzon M, Brozek I, Limon J, Housman DE, Pelletier J, Zabel B. |
Proc Natl Acad Sci U S A. 2005 Mar 15;102(11):4085-90. Epub 2005 Mar 2. |
PMID 15743916 |
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High-resolution analysis of 16q22.1 in breast carcinoma using DNA amplifiable probes (multiplex amplifiable probe hybridization technique) and immunohistochemistry. |
Rakha EA, Armour JA, Pinder SE, Paish CE, Ellis IO. |
Int J Cancer. 2005 May 1;114(5):720-9. |
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Expression of the transcription factor CTCF in invasive breast cancer: a candidate gene located at 16q22.1. |
Rakha EA, Pinder SE, Paish CE, Ellis IO. |
Br J Cancer. 2004 Oct 18;91(8):1591-6. |
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Epigenetic boundaries of tumour suppressor gene promoters: the CTCF connection and its role in carcinogenesis. |
Recillas-Targa F, De La Rosa-Velazquez IA, Soto-Reyes E, Benitez-Bribiesca L. |
J Cell Mol Med. 2006 Jul-Sep;10(3):554-68. (REVIEW) |
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CTCF binds the proximal exonic region of hTERT and inhibits its transcription. |
Renaud S, Loukinov D, Bosman FT, Lobanenkov V, Benhattar J. |
Nucleic Acids Res. 2005 Dec 2;33(21):6850-60. Print 2005. |
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Critical DNA binding interactions of the insulator protein CTCF: a small number of zinc fingers mediate strong binding, and a single finger-DNA interaction controls binding at imprinted loci. |
Renda M, Baglivo I, Burgess-Beusse B, Esposito S, Fattorusso R, Felsenfeld G, Pedone PV. |
J Biol Chem. 2007 Nov 16;282(46):33336-45. Epub 2007 Sep 7. |
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CTCF is a DNA methylation-sensitive positive regulator of the INK/ARF locus. |
Rodriguez C, Borgel J, Court F, Cathala G, Forne T, Piette J. |
Biochem Biophys Res Commun. 2010 Feb 5;392(2):129-34. Epub 2010 Jan 4. |
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CTCF physically links cohesin to chromatin. |
Rubio ED, Reiss DJ, Welcsh PL, Disteche CM, Filippova GN, Baliga NS, Aebersold R, Ranish JA, Krumm A. |
Proc Natl Acad Sci U S A. 2008 Jun 17;105(24):8309-14. Epub 2008 Jun 11. |
PMID 18550811 |
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Role of CTCF in the regulation of microRNA expression. |
Saito Y, Saito H. |
Front Genet. 2012;3:186. doi: 10.3389/fgene.2012.00186. Epub 2012 Sep 25. |
PMID 23056006 |
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Waves of retrotransposon expansion remodel genome organization and CTCF binding in multiple mammalian lineages. |
Schmidt D, Schwalie PC, Wilson MD, Ballester B, Goncalves A, Kutter C, Brown GD, Marshall A, Flicek P, Odom DT. |
Cell. 2012 Jan 20;148(1-2):335-48. doi: 10.1016/j.cell.2011.11.058. Epub 2012 Jan 12. |
PMID 22244452 |
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CTCF maintains differential methylation at the Igf2/H19 locus. |
Schoenherr CJ, Levorse JM, Tilghman SM. |
Nat Genet. 2003 Jan;33(1):66-9. Epub 2002 Dec 2. |
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CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing. |
Shukla S, Kavak E, Gregory M, Imashimizu M, Shutinoski B, Kashlev M, Oberdoerffer P, Sandberg R, Oberdoerffer S. |
Nature. 2011 Nov 3;479(7371):74-9. doi: 10.1038/nature10442. |
PMID 21964334 |
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Genome wide ChIP-chip analyses reveal important roles for CTCF in Drosophila genome organization. |
Smith ST, Wickramasinghe P, Olson A, Loukinov D, Lin L, Deng J, Xiong Y, Rux J, Sachidanandam R, Sun H, Lobanenkov V, Zhou J. |
Dev Biol. 2009 Apr 15;328(2):518-28. Epub 2009 Jan 8. |
PMID 19210964 |
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Disruption of CTCF at the miR-125b1 locus in gynecological cancers. |
Soto-Reyes E, Gonzalez-Barrios R, Cisneros-Soberanis F, Herrera-Goepfert R, Perez V, Cantu D, Prada D, Castro C, Recillas-Targa F, Herrera LA. |
BMC Cancer. 2012 Jan 25;12:40. doi: 10.1186/1471-2407-12-40. |
PMID 22277129 |
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Mechanisms causing imprinting defects in familial Beckwith-Wiedemann syndrome with Wilms' tumour. |
Sparago A, Russo S, Cerrato F, Ferraiuolo S, Castorina P, Selicorni A, Schwienbacher C, Negrini M, Ferrero GB, Silengo MC, Anichini C, Larizza L, Riccio A. |
Hum Mol Genet. 2007 Feb 1;16(3):254-64. Epub 2006 Dec 11. |
PMID 17158821 |
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CTCF mediates long-range chromatin looping and local histone modification in the beta-globin locus. |
Splinter E, Heath H, Kooren J, Palstra RJ, Klous P, Grosveld F, Galjart N, de Laat W. |
Genes Dev. 2006 Sep 1;20(17):2349-54. |
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Large scale mapping of methylcytosines in CTCF-binding sites in the human H19 promoter and aberrant hypomethylation in human bladder cancer. |
Takai D, Gonzales FA, Tsai YC, Thayer MJ, Jones PA. |
Hum Mol Genet. 2001 Nov 1;10(23):2619-26. |
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Perturbations of the Ink4a/Arf gene locus in aflatoxin B1-induced mouse lung tumors. |
Tam AS, Devereux TR, Patel AC, Foley JF, Maronpot RR, Massey TE. |
Carcinogenesis. 2003 Jan;24(1):121-32. |
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Restraint of angiogenesis by zinc finger transcription factor CTCF-dependent chromatin insulation. |
Tang M, Chen B, Lin T, Li Z, Pardo C, Pampo C, Chen J, Lien CL, Wu L, Ai L, Wang H, Yao K, Oh SP, Seto E, Smith LE, Siemann DW, Kladde MP, Cepko CL, Lu J. |
Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15231-6. doi: 10.1073/pnas.1104662108. Epub 2011 Sep 6. |
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The cancer-testis antigen BORIS phenocopies the tumor suppressor CTCF in normal and neoplastic cells. |
Tiffen JC, Bailey CG, Marshall AD, Metierre C, Feng Y, Wang Q, Watson SL, Holst J, Rasko JE. |
Int J Cancer. 2013 Oct 1;133(7):1603-13. doi: 10.1002/ijc.28184. Epub 2013 May 2. |
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CTCF regulates growth and erythroid differentiation of human myeloid leukemia cells. |
Torrano V, Chernukhin I, Docquier F, D'Arcy V, Leon J, Klenova E, Delgado MD. |
J Biol Chem. 2005 Jul 29;280(30):28152-61. Epub 2005 Jun 6. |
PMID 15941718 |
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Targeting of CTCF to the nucleolus inhibits nucleolar transcription through a poly(ADP-ribosyl)ation-dependent mechanism. |
Torrano V, Navascues J, Docquier F, Zhang R, Burke LJ, Chernukhin I, Farrar D, Leon J, Berciano MT, Renkawitz R, Klenova E, Lafarga M, Delgado MD. |
J Cell Sci. 2006 May 1;119(Pt 9):1746-59. Epub 2006 Apr 4. |
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Loss of imprinting of IGF2 and H19 in osteosarcoma is accompanied by reciprocal methylation changes of a CTCF-binding site. |
Ulaner GA, Vu TH, Li T, Hu JF, Yao XM, Yang Y, Gorlick R, Meyers P, Healey J, Ladanyi M, Hoffman AR. |
Hum Mol Genet. 2003 Mar 1;12(5):535-49. |
PMID 12588801 |
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Widespread plasticity in CTCF occupancy linked to DNA methylation. |
Wang H, Maurano MT, Qu H, Varley KE, Gertz J, Pauli F, Lee K, Canfield T, Weaver M, Sandstrom R, Thurman RE, Kaul R, Myers RM, Stamatoyannopoulos JA. |
Genome Res. 2012b Sep;22(9):1680-8. doi: 10.1101/gr.136101.111. |
PMID 22955980 |
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De-SUMOylation of CCCTC binding factor (CTCF) in hypoxic stress-induced human corneal epithelial cells. |
Wang J, Wang Y, Lu L. |
J Biol Chem. 2012a Apr 6;287(15):12469-79. doi: 10.1074/jbc.M111.286641. Epub 2012 Feb 21. |
PMID 22354964 |
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Cohesin mediates transcriptional insulation by CCCTC-binding factor. |
Wendt KS, Yoshida K, Itoh T, Bando M, Koch B, Schirghuber E, Tsutsumi S, Nagae G, Ishihara K, Mishiro T, Yahata K, Imamoto F, Aburatani H, Nakao M, Imamoto N, Maeshima K, Shirahige K, Peters JM. |
Nature. 2008 Feb 14;451(7180):796-801. Epub 2008 Jan 30. |
PMID 18235444 |
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Modular insulators: genome wide search for composite CTCF/thyroid hormone receptor binding sites. |
Weth O, Weth C, Bartkuhn M, Leers J, Uhle F, Renkawitz R. |
PLoS One. 2010 Apr 9;5(4):e10119. |
PMID 20404925 |
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Epigenetic silencing of the p16(INK4a) tumor suppressor is associated with loss of CTCF binding and a chromatin boundary. |
Witcher M, Emerson BM. |
Mol Cell. 2009 May 15;34(3):271-84. |
PMID 19450526 |
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Specific sites in the C terminus of CTCF interact with the SA2 subunit of the cohesin complex and are required for cohesin-dependent insulation activity. |
Xiao T, Wallace J, Felsenfeld G. |
Mol Cell Biol. 2011 Jun;31(11):2174-83. doi: 10.1128/MCB.05093-11. Epub 2011 Mar 28. |
PMID 21444719 |
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CpG island methylation affects accessibility of the proximal BRCA1 promoter to transcription factors. |
Xu J, Huo D, Chen Y, Nwachukwu C, Collins C, Rowell J, Slamon DJ, Olopade OI. |
Breast Cancer Res Treat. 2010 Apr;120(3):593-601. Epub 2009 May 23. |
PMID 19466541 |
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Chromosome arm 16q in Wilms tumors: unbalanced chromosomal translocations, loss of heterozygosity, and assessment of the CTCF gene. |
Yeh A, Wei M, Golub SB, Yamashiro DJ, Murty VV, Tycko B. |
Genes Chromosomes Cancer. 2002 Oct;35(2):156-63. |
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Rasgrf1 imprinting is regulated by a CTCF-dependent methylation-sensitive enhancer blocker. |
Yoon B, Herman H, Hu B, Park YJ, Lindroth A, Bell A, West AG, Chang Y, Stablewski A, Piel JC, Loukinov DI, Lobanenkov VV, Soloway PD. |
Mol Cell Biol. 2005 Dec;25(24):11184-90. |
PMID 16314537 |
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Poly(ADP-ribosyl)ation regulates CTCF-dependent chromatin insulation. |
Yu W, Ginjala V, Pant V, Chernukhin I, Whitehead J, Docquier F, Farrar D, Tavoosidana G, Mukhopadhyay R, Kanduri C, Oshimura M, Feinberg AP, Lobanenkov V, Klenova E, Ohlsson R. |
Nat Genet. 2004 Oct;36(10):1105-10. Epub 2004 Sep 7. |
PMID 15361875 |
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CTCF tethers an insulator to subnuclear sites, suggesting shared insulator mechanisms across species. |
Yusufzai TM, Tagami H, Nakatani Y, Felsenfeld G. |
Mol Cell. 2004 Jan 30;13(2):291-8. |
PMID 14759373 |
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Dynamic association of the mammalian insulator protein CTCF with centrosomes and the midbody. |
Zhang R, Burke LJ, Rasko JE, Lobanenkov V, Renkawitz R. |
Exp Cell Res. 2004 Mar 10;294(1):86-93. |
PMID 14980504 |
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CCCTC-binding factor acts upstream of FOXA1 and demarcates the genomic response to estrogen. |
Zhang Y, Liang J, Li Y, Xuan C, Wang F, Wang D, Shi L, Zhang D, Shang Y. |
J Biol Chem. 2010 Sep 10;285(37):28604-13. doi: 10.1074/jbc.M110.149658. Epub 2010 Jul 7. |
PMID 20610384 |
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A screen for germline mutations in the gene encoding CCCTC-binding factor (CTCF) in familial non-BRCA1/BRCA2 breast cancer. |
Zhou XL, Werelius B, Lindblom A. |
Breast Cancer Res. 2004;6(3):R187-90. Epub 2004 Mar 9. |
PMID 15084242 |
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CTCFBSDB 2.0: a database for CTCF-binding sites and genome organization. |
Ziebarth JD, Bhattacharya A, Cui Y. |
Nucleic Acids Res. 2013 Jan;41(Database issue):D188-94. doi: 10.1093/nar/gks1165. Epub 2012 Nov 27. |
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Transcriptional element H4-site II of cell cycle regulated human H4 histone genes is a multipartite protein/DNA interaction site for factors HiNF-D, HiNF-M, and HiNF-P: involvement of phosphorylation. |
van Wijnen AJ, Ramsey-Ewing AL, Bortell R, Owen TA, Lian JB, Stein JL, Stein GS. |
J Cell Biochem. 1991 Jun;46(2):174-89. |
PMID 1655821 |
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