1.Department of Pathology, Peking University Peoples Hospital, Beijing 100044, Peoples Republic of Chinae, chendingbao@21cn.com
Post-transplant lymphoproliferative disorders (PTLDs) are serious, life-threatening complications of transplantation, which represent a heterogeneous group of lymphoproliferative diseases and show a spectrum of clinical, morphologic, and molecular genetic features ranging from reactive polyclonal lesions to frank lymphomas. Polymorphic(P) PTLD are composed of immunoblasts, plasma cells and small and intermediate-sized lymphoid cells that efface the architecture of lymph nodes or form destructive extranodal masses and do not fulfill the criteria for any of the recognized types of lymphoma described in immunocompetent hosts, which shows characteristic clinicopathological features and molecular involvement.
Ding-Bao Chen
Polymorphic PTLD
Atlas Genet Cytogenet Oncol Haematol. 2017-04-01
Online version: http://atlasgeneticsoncology.org/haematological/1751/polymorphic-ptld