1.Cytogenetic laboratory, Pathology Department; Detroit Medical Center, Wayne State University School of Medicine, Detroit, USA
Leukemia
Age/Sex
WBC 109/L
Karyotype
Fusion Genes
Outcome
References
1
T-ALL L1
21/M
423
46,XY,t(4;11)(q21;p15),+2mar
NUP98/RAP1GDS1
Relapsed after 2 matched BMT; died 43 M
Hussey et al., 1999
2
25/F
1.8
46,XX,t(4;11)(q21;p14-15), del(12)(p13),+del(13)(q12q14)
Failure of induction; Died 1M later
3
T-ALL L2
49/M
169
46,XY,t(4;11)(q21;p15),del(5)(q13q31)
BM remission, early relapse, died 14 M
4
16/F
34
47,XX,t(4;11)(q21;p15),+8
CR, followed by BMT; 7 m+
Mecucci et al., 2000
5
38F
35
47,XX,t(4;11)(q21;p15),+mar
CR, relapsed in 8 m; died after BMT
Mecucci et al. 2000
6
AML-M0
60/F
3.9
46- t(4;11)(q1?3;p15),?der(8)(p?)
CR; relapsed and died 8m after diagnosis
van Zutven et al, 2006
7
T-ALL
15/M
72.8
46,XY,t(4;11)(q23;p15),del(9)(p13)
CR obtained, survival 7M+
Present case, 2015
Anwar N Mohamed
t(4;11)(q23;p15) NUP98/RAP1GDS1
Atlas Genet Cytogenet Oncol Haematol. 2016-01-01
Online version: http://atlasgeneticsoncology.org/haematological/1191/js/lib/cancer-prone-explorer/img/logo-atlas-4.svg
2002-07-01 t(4;11)(q23;p15) NUP98/RAP1GDS1 by Franck Viguié  Affiliation