1.Department of Diagnostic Pathology and Laboratory Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy. annunziata.gloghini@istitutotumori.mi.it (AG); Department of Pathology Centro di Riferimento Oncologico Aviano (CRO), Istituto Nazionale Tumori, IRCCS, Aviano, Italy. acarbone@cro.it (AC); Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania. pantanowitzl@upmc.edu (LP)2.Department of Diagnostic Pathology and Laboratory Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy. annunziata.gloghini@istitutotumori.mi.it (AG); Department of Pathology Centro di Riferimento Oncologico Aviano (CRO), Istituto Nazionale Tumori, IRCCS, Aviano, Italy. acarbone@cro.it (AC); Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania. pantanowitzl@upmc.edu (LP)
Lymphoma remains the most frequent neoplastic cause of death among HIV-infected individuals.
Burkitt lymphoma- mostly plasmacytoid
Primary central nervous system lymphoma
Diffuse large B-cell lymphoma, including primary central nervous system lymphoma (immunoblastic, plasmacytoid and centroblastic)
Plasmablastic lymphoma
Primary effusion lymphoma (PEL) and its solid variant (Classic PEL - in the absence of tumor masses; Solid PEL with or without serous effusion)
Multicentric Castleman Disease (MCD)-associated large cell lymphoma
Hodgkin lymphoma
Other histotypes (rare)
Marginal zone lymphoma
Unclassifiable lymphomas with features intermediate between Burkitt lymphoma and diffuse large B-cell lymphoma
Polymorphic B-cell lymphoma (PTLD-like)
BL
DLBCL-CB
DLBCL-IB
PBL
PEL
Viral Infection
EBV
+/-
-/+
+
KSHV
-
Genetic abnormalities
BCL2
30%
20%
Antonino Carbone ; Liron Pantanowitz ; Annunziata Gloghini
HIV-associated lymphomas
Atlas Genet Cytogenet Oncol Haematol. 2016-05-01
Online version: http://atlasgeneticsoncology.org/haematological/1732/js/lib/favicon/welcome