1.Lymphoma Research Laboratory, Department of Medicine, Gordon H. Scott Hall for Basic Medical Sciences, Room #8229, 540 East Canfield (AMAK) and the Cytogenetics Laboratory, Department of Pathology, email@example.com (ANM), Wayne State University School of Medicine, Detroit, MI 48202 USA
Primary cutaneous B-cell lymphomas (PCBCL) are a heterogeneous group of mature B-cells neoplasms that present in the skin without evidence of nodal or systemic involvement. The clinical and pathologic features of PCBCL differ significantly from the equivalent nodal lymphomas. Three main subtypes of PCBCL are recognized by the 2016 revised WHO classification. Studies have shown that PCBCLs are characterized by distinct immunophenotypic features, chromosomal aberrations and gene rearrangements which provide further support for their classification as separate entities from their nodal types.
Ayad M. Al-Katib ; Anwar N. Mohamed
Primary Cutaneous B-Cell Lymphomas
Atlas Genet Cytogenet Oncol Haematol. 2019-07-01
Online version: http://atlasgeneticsoncology.org/haematological/1851/primary-cutaneous-b-cell-lymphomas