- Variant 1 differs in the 5 UTR and coding sequence compared to variant 2. The resulting isoform (a) is shorter at the N-terminus compared to isoform (b).
4414 bp - 33 exons - 1065 aa.
Ave. residue weight: 113.521.
Isoelectric point: 6.7311.
Molecular weight: 120899.54.
Number of residues: 1065.
- Variant 2 encodes the longest isoform (b).
4286 bp - 31 exons - 1073 aa.
Ave. residue weight: 113.366.
Isoelectric point: 6.6317.
Molecular weight: 121641.45.
Number of residues: 1073.
- Variant 3 differs in the 5 UTR and coding sequence, and contains two additional in-frame segments near the 3 end of the coding sequence, compared to variant 2. The resulting isoform (c) is shorter at the N-terminus and contains two additional segments in the C-terminus compared to isoform b.
Joerg Schwock ; Neesha Dhani
PTK2 (PTK2 protein tyrosine kinase 2)
Atlas Genet Cytogenet Oncol Haematol. 2011-03-01
Online version: http://atlasgeneticsoncology.org/gene/41898/ptk2-(ptk2-protein-tyrosine-kinase-2)